[4-(p-Hydroxyphenoxy)-3,5-diiodophenyl]acetic Acid
3,5-DIIODOTHYROACETIC ACID
CAS: 1155-40-4
Molecular Formula: C14H10I2O4
[4-(p-Hydroxyphenoxy)-3,5-diiodophenyl]acetic Acid - Names and Identifiers
[4-(p-Hydroxyphenoxy)-3,5-diiodophenyl]acetic Acid - Physico-chemical Properties
| Molecular Formula | C14H10I2O4 |
| Molar Mass | 496.04 |
| Density | 2.156±0.06 g/cm3(Predicted) |
| Melting Point | 223.5-225.0 °C(Solv: water (7732-18-5); acetic acid (64-19-7)) |
| Boling Point | 527.8±50.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | Off-White to Pale Brown |
| pKa | 4.10±0.10(Predicted) |
| Storage Condition | 2-8°C |
[4-(p-Hydroxyphenoxy)-3,5-diiodophenyl]acetic Acid - Upstream Downstream Industry
[4-(p-Hydroxyphenoxy)-3,5-diiodophenyl]acetic Acid - Introduction
3,5-diiodothyroacetic ACID, also known as 3,5-diiodothyroacetic acid, is an organic compound.
Nature:
-Appearance: White or light yellow crystal
-Melting point: 220-222 ° C
-Molecular formula: C10H7I2O4
-Molecular Weight: 472.97
Use:
3,5-Diiodothyroacetic acid is a thyroid hormone. It is mainly used in scientific research as a non-selective thyroxine antagonist, which can interfere with the action of thyroid hormones. It can also be used as an intermediate in the preparation of other drugs.
Method:
A commonly used preparation method is through the iodination reaction of p-hydroxyphenoxybenzoic acid, and then acetylation to obtain 3,5-diiodothyroacetic acid.
Safety Information:
3,5-Diiodothyroacetic acid is relatively stable under proper handling and storage conditions. However, it is still a toxic compound and should be used with caution. During operation, wear appropriate protective equipment, such as laboratory gloves, eye protection glasses, etc. When using or handling the compound, follow relevant safety practices and ensure proper ventilation.
Nature:
-Appearance: White or light yellow crystal
-Melting point: 220-222 ° C
-Molecular formula: C10H7I2O4
-Molecular Weight: 472.97
Use:
3,5-Diiodothyroacetic acid is a thyroid hormone. It is mainly used in scientific research as a non-selective thyroxine antagonist, which can interfere with the action of thyroid hormones. It can also be used as an intermediate in the preparation of other drugs.
Method:
A commonly used preparation method is through the iodination reaction of p-hydroxyphenoxybenzoic acid, and then acetylation to obtain 3,5-diiodothyroacetic acid.
Safety Information:
3,5-Diiodothyroacetic acid is relatively stable under proper handling and storage conditions. However, it is still a toxic compound and should be used with caution. During operation, wear appropriate protective equipment, such as laboratory gloves, eye protection glasses, etc. When using or handling the compound, follow relevant safety practices and ensure proper ventilation.
Last Update：2024-04-09 20:45:29
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View History
Raw Materials for [4-(p-Hydroxyphenoxy)-3,5-diiodophenyl]acetic Acid
ethyl 2-(4-hydroxy-3,5-dinitrophenyl)acetate
4-HYDROXYPHENYL BENZOATE
4-Benzyloxyphenol
4-Hydroxyphenylacetic acid
4-Methoxyphenylboronic acid
Hydroquinone
4-HYDROXYPHENYL BENZOATE
4-Benzyloxyphenol
4-Hydroxyphenylacetic acid
4-Methoxyphenylboronic acid
Hydroquinone